Nanocellulose is a term referring to a family of cellulosic materials that have at least one of their dimensions in the nanoscale. Examples of nanocellulosic materials are microfibrilated cellulose, cellulose nanofibers or cellulose nanocrystals. Nanocellulose may be obtained from natural cellulose fibers through a variety of production processes. This family of materials possesses interesting properties suitable for a wide range of potential applications.

Terminology

Microfibrilated cellulose

Micro cellulose (MFC) is a type of nanocellulose that is more heterogeneous than cellulose nanofibers or nanocrystals as it contains a mixture of nano- and micro-scale particles. The term is sometimes misused to refer to cellulose nanofibers instead.[1][2]

Cellulose nanofibers

Cellulose nanofibers (CNF), also called nanofibrillated cellulose (NFC), are nanosized cellulose fibrils with a high aspect ratio (length to width ratio). Typical fibril widths are 5–20 nanometers with a wide range of lengths, typically several micrometers.

The fibrils can be isolated from natural cellulose, generally wood pulp, produced by mechanical fibrillation of cellulose fibres through high-pressure, high temperature and high velocity impact homogenization, grinding or microfluidization (see manufacture).[3][4][5]

Cellulose nanocrystals

Cellulose nanocrystals (CNCs), or nanocrystalline cellulose (NCC), are highly crystalline, rod-like nanoparticles.[6][7] They are usually covered by negatively charged groups that render them colloidally stable in water. They are typically shorter than CNFs, with a typical length of 100 to 1000 nanometers.[8]

Bacterial nanocellulose

Some cellulose producing bacteria have also been used to produce nanocellulosic materials that are then referred to as bacterial nanocellulose.[9] The most common examples being Medusomyces gisevii (the bacteria involved in the making of Kombucha) and Komagataeibacter xylinus (involve in the fabrication of Nata de coco), see bacterial cellulose for more details. This naming distinction might arise from the very peculiar morphology of these materials compared to the more traditional ones made of wood or cotton cellulose. In practice, bacterial nanocellulosic materials are often larger than their wood or cotton counterparts.

History

The discovery of nanocellulosic materials can be traced back to late 1940s studies on the hydrolysis of cellulose fibers.[2] Eventually it was noticed that cellulose hydrolysis seemed to occur preferentially at some disordered intercrystalline portions of the fibers.[10] This led to the obtention of colloidally stable and highly crystalline nanorods particles.[11][12][13] These particles were first referred to as micelles, before being given multiple names including cellulose nanocrystals (CNCs), nanocrystalline cellulose (NCC), or cellulose (nano)whiskers, though this last term is less used today.[2] Later studies by O. A. Battista showed that in milder hydrolysis conditions, the crystalline nanorods stay aggregated as micron size objects.[14][15] This material was later referred to as microcrystalline cellulose (MCC) and commercialised under the name Avicel by FMC Corporation.[16]

Microfibrillated cellulose (MFC) was discovered later, in the 1980s, by Turbak, Snyder and Sandberg at the ITT Rayonier labs in Shelton, Washington.[17][18][19] This terminology was used to describe a gel-like material prepared by passing wood pulp through a Gaulin type milk homogenizer at high temperatures and high pressures followed by ejection impact against a hard surface. In later work, F. W. Herrick at ITT Rayonier Eastern Research Division (ERD) Lab in Whippany also published work on making a dry powder form of the gel.[20][19] Rayonier, as a company, never pursued scale-up and gave free license to whoever wanted to pursue this new use for cellulose.[citation needed] Rather, Turbak et al. pursued 1) finding new uses for the MFC, including using as a thickener and binder in foods, cosmetics, paper formation, textiles, nonwovens, etc. and 2) evaluate swelling and other techniques for lowering the energy requirements for MFC production.[21] The first MFC pilot production plant of MFC was established in 2010 by Innventia AB (Sweden).[22]

Manufacture

Cellulose sources

Nanocellulose materials can be prepared from any natural cellulose source including wood, cotton, agricultural[23] or household wastes,[24] algae,[25] bacteria or tunicate. Wood, in the form of wood pulp is currently the most commonly used starting material for the industrial production of nanocellulosic materials.

Nanocellulose fibrils

Nanocellulose fibrils (MFC and CNFs) may be isolated from the cellulose fibers using mechanical methods that expose the fibers to high shear forces, delaminating them into nano-fibers. For this purpose, high-pressure homogenizers, grinders or microfluidizers can be used.[26] This process consumes very large amounts of energy and values over 30 MWh/tonne are not uncommon.[citation needed]

To address this problem, sometimes enzymatic/mechanical pre-treatments and introduction of charged groups for example through carboxymethylation or TEMPO-mediated oxidation are used.[27] These pre-treatments can decrease energy consumption below 1 MWh/tonne.[citation needed] "Nitro-oxidation" has been developed to prepare carboxycellulose nanofibers directly from raw plant biomass. Owing to fewer processing steps to extract nanocellulose, the nitro-oxidation method has been found to be a cost-effective, less-chemically oriented and efficient method to extract carboxycellulose nanofibers.[28][29] Functionalized nanofibers obtained using nitro-oxidation have been found to be an excellent substrate to remove heavy metal ion impurities such as lead,[30] cadmium,[31] and uranium.[32]

A chemo-mechanical process for production of nanocellulose from cotton linters has been demonstrated with a capacity of 10 kg per day.[33]

Cellulose nanocrystals

Cellulose nanocrystals (CNC) are rod like particles formed by the acid hydrolysis of native cellulose fibers, most commonly using sulfuric or hydrochloric acid. Disordered sections of native cellulose are hydrolysed and after careful timing, the remaining crystalline sections can be retrieved from the acid solution by centrifugation and dialysis against water. Their final dimensions depend on the cellulose source, its history, the hydrolysis conditions and the purification procedures.[34] CNCs are commercialised by various companies that use different sources and processes, leading to a range of available products.[35][36]

Other cellulose based nanoparticles

Spherical shaped carboxycellulose nanoparticles prepared by nitric acid-phosphoric acid treatment are stable in dispersion in its non-ionic form.[37]

Structure and properties

Dimensions and crystallinity

The ultrastructure of nanocellulose derived from various sources has been extensively studied. Techniques such as transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscopy (AFM), wide angle X-ray scattering (WAXS), small incidence angle X-ray diffraction and solid state 13C cross-polarization magic angle spinning (CP/MAS), nuclear magnetic resonance (NMR) and spectroscopy have been used to characterize typically dried nanocellulose morphology.[citation needed]

A combination of microscopic techniques with image analysis can provide information on fibril widths, it is more difficult to determine fibril lengths, because of entanglements and difficulties in identifying both ends of individual nanofibrils.[38][39] Also, nanocellulose suspensions may not be homogeneous and can consist of various structural components, including cellulose nanofibrils and nanofibril bundles.[40]

In a study of enzymatically pre-treated nanocellulose fibrils in a suspension the size and size-distribution were established using cryo-TEM. The fibrils were found to be rather mono-dispersed mostly with a diameter of ca. 5 nm although occasionally thicker fibril bundles were present.[41] By combining ultrasonication with an "oxidation pretreatment", cellulose microfibrils with a lateral dimension below 1 nm has been observed by AFM. The lower end of the thickness dimension is around 0.4 nm, which is related to the thickness of a cellulose monolayer sheet.[42]

Aggregate widths can be determined by CP/MAS NMR developed by Innventia AB, Sweden, which also has been demonstrated to work for nanocellulose (enzymatic pre-treatment). An average width of 17 nm has been measured with the NMR-method, which corresponds well with SEM and TEM. Using TEM, values of 15 nm have been reported for nanocellulose from carboxymethylated pulp. However, thinner fibrils can also be detected. Wågberg et al. reported fibril widths of 5–15 nm for a nanocellulose with a charge density of about 0.5 meq./g.[43] The group of Isogai reported fibril widths of 3–5 nm for TEMPO-oxidized cellulose having a charge density of 1.5 meq./g.[44]

Pulp chemistry has a significant influence on nanocellulose microstructure. Carboxymethylation increases the numbers of charged groups on the fibril surfaces, making the fibrils easier to liberate and results in smaller and more uniform fibril widths (5–15 nm) compared to enzymatically pre-treated nanocellulose, where the fibril widths were 10–30 nm.[45]

The degree of crystallinity and crystal structure of nanocellulose.

Nanocellulose exhibits cellulose crystal I organization and the degree of crystallinity is unchanged by the preparation of the nanocellulose. Typical values for the degree of crystallinity were around 63%.[45]

Viscosity

The rheology of nanocellulose dispersions has been investigated.[46][41] and revealed that the storage and loss modulus were independent of the angular frequency at all nanocellulose concentrations between 0.125% to 5.9%. The storage modulus values are particularly high (104 Pa at 3% concentration)[41] compared to results for CNCs (102 Pa at 3% concentration).[46] There is also a strong concentration dependence as the storage modulus increases 5 orders of magnitude if the concentration is increased from 0.125% to 5.9%. Nanocellulose gels are also highly shear thinning (the viscosity is lost upon introduction of the shear forces). The shear-thinning behaviour is particularly useful in a range of different coating applications.[41]

It is pseudo-plastic and exhibits thixotropy, the property of certain gels or fluids that are thick (viscous) under normal conditions, but become less viscous when shaken or agitated. When the shearing forces are removed the gel regains much of its original state.

Mechanical properties

Crystalline cellulose has a stiffness about 140–220 GPa, comparable with that of Kevlar and better than that of glass fiber, both of which are used commercially to reinforce plastics. Films made from nanocellulose have high strength (over 200 MPa), high stiffness (around 20 GPa)[47] but lack of high strain[clarification needed] (12%). Its strength/weight ratio is 8 times that of stainless steel.[48] Fibers made from nanocellulose have high strength (up to 1.57 GPa) and stiffness (up to 86 GPa).[49]

Barrier properties

In semi-crystalline polymers, the crystalline regions are considered to be gas impermeable. Due to relatively high crystallinity,[45] in combination with the ability of the nanofibers to form a dense network held together by strong inter-fibrillar bonds (high cohesive energy density), it has been suggested that nanocellulose might act as a barrier material.[44][50][51] Although the number of reported oxygen permeability values are limited, reports attribute high oxygen barrier properties to nanocellulose films. One study reported an oxygen permeability of 0.0006 (cm3 μm)/(m2 day kPa) for a ca. 5 μm thin nanocellulose film at 23 °C and 0% RH.[50] In a related study, a more than 700-fold decrease in oxygen permeability of a polylactide (PLA) film when a nanocellulose layer was added to the PLA surface was reported.[44]

The influence of nanocellulose film density and porosity on film oxygen permeability has been explored.[52] Some authors have reported significant porosity in nanocellulose films,[53][47][54] which seems to be in contradiction with high oxygen barrier properties, whereas Aulin et al.[50] measured a nanocellulose film density close to density of crystalline cellulose (cellulose Iß crystal structure, 1.63 g/cm3)[55] indicating a very dense film with a porosity close to zero.

Changing the surface functionality of the cellulose nanoparticle can also affect the permeability of nanocellulose films. Films constituted of negatively charged CNCs could effectively reduce permeation of negatively charged ions, while leaving neutral ions virtually unaffected. Positively charged ions were found to accumulate in the membrane.[56]

Multi-parametric surface plasmon resonance is one of the methods to study barrier properties of natural, modified or coated nanocellulose. The different antifouling, moisture, solvent, antimicrobial barrier formulation quality can be measured on the nanoscale. The adsorption kinetics as well as the degree of swelling can be measured in real-time and label-free.[57][58]

Liquid crystals, colloidal glasses, and hydrogels

Owed to their anisotropic shape and surface charge, nanocelluloses (mostly rigid CNCs) have a high excluded volume and self-assemble into cholesteric liquid crystals beyond a critical volume fraction.[59] Nanocellulose liquid crystals are left-handed due to the right-handed twist on particle level.[60] Nanocellulose phase behavior is susceptible to ionic charge screening. An increase in ionic strength induces the arrest of nanocellulose dispersions into attractive glasses.[61] At further increasing ionic strength, nanocelluloses aggregate into hydrogels.[62] The interactions within nanocelluloses are weak and reversible, wherefore nanocellulose suspensions and hydrogels are self-healing and may be applied as injectable materials[63] or 3D printing inks.[64]

Bulk foams and aerogels

Nanocellulose can also be used to make aerogels/foams, either homogeneously or in composite formulations. Nanocellulose-based foams are being studied for packaging applications in order to replace polystyrene-based foams. Svagan et al. showed that nanocellulose has the ability to reinforce starch foams by using a freeze-drying technique.[65] The advantage of using nanocellulose instead of wood-based pulp fibers is that the nanofibrils can reinforce the thin cells in the starch foam. Moreover, it is possible to prepare pure nanocellulose aerogels applying various freeze-drying and super critical CO2 drying techniques. Aerogels and foams can be used as porous templates.[66][67] Tough ultra-high porosity foams prepared from cellulose I nanofibril suspensions were studied by Sehaqui et al. a wide range of mechanical properties including compression was obtained by controlling density and nanofibril interaction in the foams.[68] CNCs could also be made to gel in water under low power sonication giving rise to aerogels with the highest reported surface area (>600m2/g) and lowest shrinkage during drying (6.5%) of cellulose aerogels.[67] In another study by Aulin et al.,[69] the formation of structured porous aerogels of nanocellulose by freeze-drying was demonstrated. The density and surface texture of the aerogels was tuned by selecting the concentration of the nanocellulose dispersions before freeze-drying. Chemical vapour deposition of a fluorinated silane was used to uniformly coat the aerogel to tune their wetting properties towards non-polar liquids/oils. The authors demonstrated that it is possible to switch the wettability behaviour of the cellulose surfaces between super-wetting and super-repellent, using different scales of roughness and porosity created by the freeze-drying technique and change of concentration of the nanocellulose dispersion. Structured porous cellulose foams can however also be obtained by utilizing the freeze-drying technique on cellulose generated by Gluconobacter strains of bacteria, which bio-synthesize open porous networks of cellulose fibers with relatively large amounts of nanofibrils dispersed inside. Olsson et al.[70] demonstrated that these networks can be further impregnated with metalhydroxide/oxide precursors, which can readily be transformed into grafted magnetic nanoparticles along the cellulose nanofibers. The magnetic cellulose foam may allow for a number of novel applications of nanocellulose and the first remotely actuated magnetic super sponges absorbing 1 gram of water within a 60 mg cellulose aerogel foam were reported. Notably, these highly porous foams (>98% air) can be compressed into strong magnetic nanopapers, which may find use as functional membranes in various applications.

Pickering emulsions and foams

Nanocelluloses can stabilize emulsions and foams by a Pickering mechanism, i.e. they adsorb at the oil-water or air-water interface and prevent their energetic unfavorable contact. Nanocelluloses form oil-in-water emulsions with a droplet size in the range of 4-10 μm that are stable for months and can resist high temperatures and changes in pH.[71][72] Nanocelluloses decrease the oil-water interface tension[73] and their surface charge induces electrostatic repulsion within emulsion droplets. Upon salt-induced charge screening the droplets aggregate but do not undergo coalescence, indicating strong steric stabilization.[74] The emulsion droplets even remain stable in the human stomach and resist gastric lipolysis, thereby delaying lipid absorption and satiation.[75][76] In contrast to emulsions, native nanocelluloses are generally not suitable for the Pickering stabilization of foams, which is attributed to their primarily hydrophilic surface properties that results in an unfavorable contact angle below 90° (they are preferably wetted by the aqueous phase).[77] Using hydrophobic surface modifications or polymer grafting, the surface hydrophobicity and contact angle of nanocelluloses can be increased, allowing also the Pickering stabilization of foams.[78] By further increasing the surface hydrophobicity, inverse water-in-oil emulsions can be obtained, which denotes a contact angle higher than 90°.[79][80] It was further demonstrated that nanocelluloses can stabilize water-in-water emulsions in presence of two incompatible water-soluble polymers.[81]

Cellulose nanofiber plate

A bottom up approach can be used to create a high-performance bulk material with low density, high strength and toughness, and great thermal dimensional stability: cellulose nanofiber plate (CNFP). Cellulose nanofiber hydrogel is created by biosynthesis. The hydrogels can then be treated with a polymer solution or by surface modification and then are hot-pressed at 80 °C. The result is bulk material with excellent machinability. "The ultrafine nanofiber network structure in CNFP results in more extensive hydrogen bonding, the high in-plane orientation, and "three way branching points" of the microfibril networks".[82] This structure gives CNFP its high strength by distributing stress and adding barriers to crack formation and propagation. The weak link in this structure is bond between the pressed layers which can lead to delamination. To reduce delamination, the hydrogel can be treated with silicic acid, which creates strong covalent cross-links between layers during hot pressing.[82]

Surface modification

The surface modification of nanocellulose is currently receiving a large amount of attention.[83] Nanocellulose displays a high concentration of hydroxyl groups at the surface which can be reacted. However, hydrogen bonding strongly affects the reactivity of the surface hydroxyl groups. In addition, impurities at the surface of nanocellulose such as glucosidic and lignin fragments need to be removed before surface modification to obtain acceptable reproducibility between different batches.[84]

Safety aspects

Processing of nanocellulose does not cause significant exposure to fine particles during friction grinding or spray drying. No evidence of inflammatory effects or cytotoxicity on mouse or human macrophages can be observed after exposure to nanocellulose. The results of toxicity studies suggest that nanocellulose is not cytotoxic and does not cause any effects on inflammatory system in macrophages. In addition, nanocellulose is not acutely toxic to Vibrio fischeri in environmentally relevant concentrations.[85]

Despite intensified research on oral food or pharmaceutical formulations containing nanocelluloses they are not generally recognized as safe. Nanocelluloses were demonstrated to exhibit limited toxicity and oxidative stress in in vitro intestinal epithelium[86][87][88] or animal models.[89][90][91]

Potential applications

The properties of nanocellulose (e.g. mechanical properties, film-forming properties, viscosity etc.) makes it an interesting material for many applications.[92]

Paper and paperboard

In the area of paper and paperboard manufacture, nanocelluloses are expected to enhance the fiber-fiber bond strength and, hence, have a strong reinforcement effect on paper materials.[93][94][95][96] Nanocellulose may be useful as a barrier in grease-proof type of papers and as a wet-end additive to enhance retention, dry and wet strength in commodity type of paper and board products.[97][98][99][100] Grease-proofness by using a mineral oil simulant (heptane) has been demonstrated using heptane vapor rate testing.[101][102] It has been shown that applying CNF as a coating material on the surface of paper and paperboard improves the barrier properties, especially air resistance[103] and grease/oil resistance.[103][104][97] It also enhances the structure properties of paperboards (smoother surface).[105] Very high viscosity of MFC/CNF suspensions at low solids content limits the type of coating techniques that can be utilized to apply these suspensions onto paper/paperboard. Some of the coating methods utilized for MFC surface application onto paper/paperboard have been rod coating,[98] size press,[104] spray coating,[106] foam coating [107] and slot-die coating.[103] Wet-end surface application of mineral pigments and MFC mixture to improve barrier, mechanical and printing properties of paperboard are also being explored.[108]

Nanocellulose can be used to prepare flexible and optically transparent paper. Such paper is an attractive substrate for electronic devices because it is recyclable, compatible with biological objects, and easily biodegrades.[109]

Composite

As described above the properties of the nanocellulose makes an interesting material for reinforcing plastics. Nanocellulose can be spun into filaments that are stronger and stiffer than spider silk.[49][110] Nanocellulose has been reported to improve the mechanical properties of thermosetting resins, starch-based matrixes, soy protein, rubber latex, poly(lactide). Hybrid cellulose nanofibrils-clay minerals composites present interesting mechanical, gas barrier and fire retardancy properties.[111] The composite applications may be for use as coatings and films,[112] paints, foams, packaging.

Food

Nanocellulose can be used as a low calorie replacement for carbohydrate additives used as thickeners, flavour carriers, and suspension stabilizers in a wide variety of food products.[113] It is useful for producing fillings, crushes, chips, wafers, soups, gravies, puddings etc. The food applications arise from the rheological behaviour of the nanocellulose gel.

Hygiene and absorbent products

Applications in this field include: super water absorbent material (e.g. for incontinence pads material), nanocellulose used together with super absorbent polymers, nanocellulose in tissue, non-woven products or absorbent structures and as antimicrobial films.[citation needed]

Emulsion and dispersion

Nanocellulose has potential applications in the general area of emulsion and dispersion applications in other fields.[114][115]

Medical, cosmetic and pharmaceutical

The use of nanocellulose in cosmetics and pharmaceuticals has been suggested:

  • Freeze-dried nanocellulose aerogels used in sanitary napkins, tampons, diapers or as wound dressing
  • The use of nanocellulose as a composite coating agent in cosmetics e.g. for hair, eyelashes, eyebrows or nails
  • A dry solid nanocellulose composition in the form of tablets for treating intestinal disorders
  • Nanocellulose films for screening of biological compounds and nucleic acids encoding a biological compound
  • Filter medium partly based on nanocellulose for leukocyte free blood transfusion
  • A buccodental formulation, comprising nanocellulose and a polyhydroxylated organic compound
  • Powdered nanocellulose has also been suggested as an excipient in pharmaceutical compositions
  • Nanocellulose in compositions of a photoreactive noxious substance purging agent
  • Elastic cryo-structured gels for potential biomedical and biotechnological application[116]
  • Matrix for 3D cell culture

Bio-based electronics and energy storage

Nanocellulose can pave the way for a new type of "bio-based electronics" where interactive materials are mixed with nanocellulose to enable the creation of new interactive fibers, films, aerogels, hydrogels and papers.[117] E.g. nanocellulose mixed with conducting polymers such as PEDOT:PSS show synergetic effects resulting in extraordinary[118] mixed electronic and ionic conductivity, which is important for energy storage applications. Filaments spun from a mix of nanocellulose and carbon nanotubes show good conductivity and mechanical properties.[119] Nanocellulose aerogels decorated with carbon nanotubes can be constructed into robust compressible 3D supercapacitor devices.[120][121] Structures from nanocellulose can be turned into bio-based triboelectric generators[122] and sensors.

In April 2013 breakthroughs in nanocellulose production, by algae, were announced at an American Chemical Society conference, by speaker R. Malcolm Brown, Jr., Ph.D, who has pioneered research in the field for more than 40 years, spoke at the First International Symposium on Nanocellulose, part of the American Chemical Society meeting. Genes from the family of bacteria that produce vinegar, Kombucha tea and nata de coco have become stars in a project — which scientists said has reached an advanced stage - that would turn algae into solar-powered factories for producing the "wonder material" nanocellulose.[9]

Bio-based coloured materials

Cellulose nanocrystals have shown the possibility to self organize into chiral nematic structures[123] with angle-dependent iridescent colours. It is thus possible to manufacture totally bio-based pigments and glitters, films including sequins having a metallic glare and a small footprint compared to fossil-based alternatives.

Other potential applications

  • As a highly scattering material for ultra-white coatings[124]
  • Activate the dissolution of cellulose in different solvents
  • Regenerated cellulose products, such as fibers films, cellulose derivatives
  • Tobacco filter additive
  • Organometallic modified nanocellulose in battery separators
  • Reinforcement of conductive materials
  • Loud-speaker membranes
  • High-flux membranes
  • Computer components[48][125]
  • Capacitors[121]
  • Lightweight body armour and ballistic glass[48]
  • Corrosion inhibitors[126][127]
  • Radio lenses [128]
  • Art Conservation[129][130][131][132]

Nanochitin is similar in its nanostructure to cellulose nanocrystals but extracted from chitin.

See also

References

  1. ^ Osong SH, Norgren S, Engstrand P (February 2016). "Processing of wood-based microfibrillated cellulose and nanofibrillated cellulose, and applications relating to papermaking: a review". Cellulose. 23 (1): 93–123. doi:10.1007/s10570-015-0798-5
  2. ^ Charreau, Hernan; L. Foresti, Maria; Vazquez, Analia (2013-01-01). "Nanocellulose Patents Trends: A Comprehensive Review on Patents on Cellulose Nanocrystals, Microfibrillated and Bacterial Cellulose". Recent Patents on Nanotechnology. 7 (1): 56–80. doi:10.2174/187221013804484854. hdl:11336/14848. PMID 22747719
  3. ^ Zhu H, Luo W, Ciesielski PN, Fang Z, Zhu JY, Henriksson G, Himmel ME, Hu L (August 2016). "Wood-Derived Materials for Green Electronics, Biological Devices, and Energy Applications". Chemical Reviews. 116 (16): 9305–9374. doi:10.1021/acs.chemrev.6b00225. PMID 27459699
  4. ^ Klemm D, Kramer F, Moritz S, Lindström T, Ankerfors M, Gray D, Dorris A (June 2011). "Nanocelluloses: a new family of nature-based materials". Angewandte Chemie. 50 (24): 5438–5466. Bibcode:2011ACIE...50.5438K. doi:10.1002/anie.201001273. PMID 21598362
  5. ^ Habibi Y (March 2014). "Key advances in the chemical modification of nanocelluloses". Chemical Society Reviews. 43 (5): 1519–1542. doi:10.1039/C3CS60204D. PMID 24316693
  6. ^ Habibi Y, Lucia LA, Rojas OJ (June 2010). "Cellulose nanocrystals: chemistry, self-assembly, and applications". Chemical Reviews. 110 (6): 3479–3500. doi:10.1021/cr900339w. PMID 20201500
  7. ^ George J, Sabapathi SN (2015-11-04). "Cellulose nanocrystals: synthesis, functional properties, and applications". Nanotechnology, Science and Applications. 8: 45–54. doi:10.2147/NSA.S64386. PMC 4639556. PMID 26604715
  8. ^ Peng BL, Dhar N, Liu HL, Tam KC (2011). "Chemistry and applications of nanocrystalline cellulose and its derivatives: A nanotechnology perspective". The Canadian Journal of Chemical Engineering. 89 (5): 1191–1206. Bibcode:2011CJChE..89.1191P. doi:10.1002/cjce.20554. Archived 2016-10-24 at the Wayback Machine. Retrieved 2012-08-28.
  9. ^ "Engineering Algae to Make the 'Wonder Material' Nanocellulose for Biofuels and More". newswise.com
  10. ^ Nickerson RF, Habrle JA (November 1947). "Cellulose Intercrystalline Structure". Industrial & Engineering Chemistry. 39 (11): 1507–1512. doi:10.1021/ie50455a024
  11. ^ Rånby BG (1949). "Aqueous Colloidal Solutions of Cellulose Micelles". Acta Chemica Scandinavica. 3: 649–650. doi:10.3891/acta.chem.scand.03-0649
  12. ^ Morehead FF (August 1950). "Ultrasonic Disintegration of Cellulose Fibers Before and After Acid Hydrolysis". Textile Research Journal. 20 (8): 549–553. doi:10.1177/004051755002000803
  13. ^ Mukherjee SM, Woods HJ (April 1953). "X-ray and electron microscope studies of the degradation of cellulose by sulphuric acid". Biochimica et Biophysica Acta. 10 (4): 499–511. doi:10.1016/0006-3002(53)90295-9. PMID 13059015
  14. ^ "Level-off D.P cellulose products". No. 2,978,446.
  15. ^ "Crystallite aggregates disintegrated in acid medium". No. 3,141,875.
  16. ^ "Our History | FMC Corp"
  17. ^ Turbak AF, Snyder FW, Sandberg KR (1983). "Microfibrillated Cellulose, a New Cellulose Product: Properties, Uses, and Commercial Potential". Journal of Applied Polymer Science: Applied Polymer Symposium. 37: 815–827.
  18. ^ "Birth of Nanocellulose"
  19. ^ "Microfibrillated cellulose". No. 4,374,702.
  20. ^ Herrick FW, Casebier RL, Hamilton JK, Sandberg KR (January 1983). "Microfibrillated cellulose: Morphology and accessibility". J. Appl. Polym. Sci.: Appl. Polym. Symp.; (United States). 37
  21. ^ Turbak, A.F., Snyder, F.W. and Sandberg, K.R. (1984) "Microfibrillated Cellulose—A New Composition of Commercial Significance," 1984 Nonwovens Symposium, Myrtle Beach, SC, Apr. 16–19. TAPPI Press, Atlanta, GA. pp 115–124.
  22. ^ Ankerfors M (2012). Microfibrillated cellulose: Energy-efficient preparation techniques and key properties (Licentiate). Sweden: Royal Institute of Technology. ISBN 978-91-7501-464-7.
  23. ^ Almashhadani AQ, Leh CP, Chan SY, Lee CY, Goh CF (June 2022). "Nanocrystalline cellulose isolation via acid hydrolysis from non-woody biomass: Importance of hydrolysis parameters". Carbohydrate Polymers. 286. doi:10.1016/j.carbpol.2022.119285. PMID 35337507
  24. ^ Abbasi A, Makhtoumi Y, Wu Y, Chen G (2024-06-01). "Characterization of cellulose nanocrystal extracted from household waste and its application for seed germination". Carbohydrate Polymer Technologies and Applications. 7. doi:10.1016/j.carpta.2023.100409
  25. ^ El Achaby M, Kassab Z, Aboulkas A, Gaillard C, Barakat A (January 2018). "Reuse of red algae waste for the production of cellulose nanocrystals and its application in polymer nanocomposites". International Journal of Biological Macromolecules. 106: 681–691. doi:10.1016/j.ijbiomac.2017.08.067. PMID 28823511
  26. ^ Moon, Robert J.; Martini, Ashlie; Nairn, John; Simonsen, John; Youngblood, Jeff (2011). "Cellulose nanomaterials review: structure, properties and nanocomposites". Chemical Society Reviews. 40 (7): 3941. doi:10.1039/c0cs00108b. ISSN 0306-0012
  27. ^ "Marcus Wallenberg Prize: 2015 – Akira Isogai, Tsuguyuki Saito, Japan, and Yoshiharu Nishiyama, France". mwp.org/. 16 March 2015. Retrieved 23 January 2018.
  28. ^ Sharma PR, Joshi R, Sharma SK, Hsiao BS (August 2017). "A Simple Approach to Prepare Carboxycellulose Nanofibers from Untreated Biomass". Biomacromolecules. 18 (8): 2333–2342. doi:10.1021/acs.biomac.7b00544. PMID 28644013
  29. ^ Sharma PR, Zheng B, Sunil KS, Zhan C, Wang R, Bhatia SR, Benjamin SH (2018). "High Aspect Ratio Carboxycellulose Nanofibers Prepared by Nitro-Oxidation Method and Their Nanopaper Properties". ACS Applied Nano Materials. 1 (8): 3969–3980. doi:10.1021/acsanm.8b00744
  30. ^ Sharma PR, Chattopadhyay A, Sunil KS, Lihong GS, Benjamin SH (2018). "Lead removal from water using carboxycellulose nanofibers prepared by nitro-oxidation method". Cellulose. 25 (3): 1961–1973. doi:10.1007/s10570-018-1659-9
  31. ^ Sharma PR, Chattopadhyay A, Sharma SK, Geng L, Amiralian N, Martin D, Hsiao BS (2018). "Nanocellulose from Spinifex as an Effective Adsorbent to Remove Cadmium(II) from Water". ACS Sustainable Chemistry & Engineering. 6 (3): 3279–3290. doi:10.1021/acssuschemeng.7b03473
  32. ^ Sharma PR, Chattopadhyay A, Sharma SK, Hsiao BS (2017). "Efficient Removal of UO22+ from Water Using Carboxycellulose Nanofibers Prepared by the Nitro-Oxidation Method". Industrial & Engineering Chemistry Research. 56 (46): 13885–13893. doi:10.1021/acs.iecr.7b03659
  33. ^ "Nanocellulose - NaNo Research GROUP @ ICAR-CIRCOT, Mumbai"
  34. ^ Hutten IM (2016). "Raw Materials for Nonwoven Filter Media". Handbook of Nonwoven Filter Media. pp. 158–275. doi:10.1016/B978-0-08-098301-1.00004-6. ISBN 978-0-08-098301-1. Cellulose nanowhiskers being a more crystalline form of nanocellulose are formed by the acid hydrolysis of native cellulose fibers commonly using sulfuric or hydrochloric acid. The amorphous sections of native cellulose are hydrolyzed and after careful timing, the crystalline sections can be retrieved from the acid solution by centrifugation and washing. Cellulose nanowhiskers are rod-like, highly crystalline particles (relative crystallinity index above 75%) with a rectangular cross section. Their dimensions depend on the native cellulose source material, hydrolysis time, and temperature.
  35. ^ Reid, Michael S.; Villalobos, Marco; Cranston, Emily D. (21 February 2017). "Benchmarking Cellulose Nanocrystals: From the Laboratory to Industrial Production". Langmuir. 33 (7): 1583–1598. doi:10.1021/acs.langmuir.6b03765. hdl:11375/21951. PMID 27959566
  36. ^ Delepierre, Gwendoline; Vanderfleet, Oriana M.; Niinivaara, Elina; Zakani, Behzad; Cranston, Emily D. (20 July 2021). "Benchmarking Cellulose Nanocrystals Part II: New Industrially Produced Materials". Langmuir. 37 (28): 8393–8409. doi:10.1021/acs.langmuir.1c00550. PMID 34250804
  37. ^ Sharma PR, Varma AJ (October 2013). "Functional nanoparticles obtained from cellulose: engineering the shape and size of 6-carboxycellulose". Chemical Communications. 49 (78): 8818–8820. doi:10.1039/c3cc44551h. PMID 23959448
  38. ^ Chinga-Carrasco G, Yu Y, Diserud O (August 2011). "Quantitative electron microscopy of cellulose nanofibril structures from Eucalyptus and Pinus radiata kraft pulp fibers". Microscopy and Microanalysis. 17 (4): 563–571. Bibcode:2011MiMic..17..563C. doi:10.1017/S1431927611000444. PMID 21740618
  39. ^ Chinga-Carrasco G, Miettinen A, Luengo Hendriks CL, Gamstedt EK, Kataja M (2011). Structural Characterisation of Kraft Pulp Fibres and Their Nanofibrillated Materials for Biodegradable Composite Applications. InTech. ISBN 978-953-307-352-1.[page needed]
  40. ^ Chinga-Carrasco G (June 2011). "Cellulose fibres, nanofibrils and microfibrils: The morphological sequence of MFC components from a plant physiology and fibre technology point of view". Nanoscale Research Letters. 6 (1). Bibcode:2011NRL.....6..417C. doi:10.1186/1556-276X-6-417. PMC 3211513. PMID 21711944
  41. ^ Pääkkö M, Ankerfors M, Kosonen H, Nykänen A, Ahola S, Osterberg M, Ruokolainen J, Laine J, Larsson PT, Ikkala O, Lindström T (June 2007). "Enzymatic hydrolysis combined with mechanical shearing and high-pressure homogenization for nanoscale cellulose fibrils and strong gels". Biomacromolecules. 8 (6): 1934–1941. doi:10.1021/bm061215p. PMID 17474776
  42. ^ Li Q, Renneckar S (March 2011). "Supramolecular structure characterization of molecularly thin cellulose I nanoparticles". Biomacromolecules. 12 (3): 650–659. doi:10.1021/bm101315y. PMID 21210665
  43. ^ Wågberg L, Decher G, Norgren M, Lindström T, Ankerfors M, Axnäs K (February 2008). "The build-up of polyelectrolyte multilayers of microfibrillated cellulose and cationic polyelectrolytes". Langmuir. 24 (3): 784–795. doi:10.1021/la702481v. PMID 18186655
  44. ^ Fukuzumi H, Saito T, Iwata T, Kumamoto Y, Isogai A (January 2009). "Transparent and high gas barrier films of cellulose nanofibers prepared by TEMPO-mediated oxidation". Biomacromolecules. 10 (1): 162–165. doi:10.1021/bm801065u. PMID 19055320
  45. ^ Aulin C, Ahola S, Josefsson P, Nishino T, Hirose Y, Osterberg M, Wågberg L (July 2009). "Nanoscale cellulose films with different crystallinities and mesostructures--their surface properties and interaction with water". Langmuir. 25 (13): 7675–7685. doi:10.1021/la900323n. PMID 19348478
  46. ^ Tatsumi D, Ishioka S, Matsumoto T (2002). "Effect of Fiber Concentration and Axial Ratio on the Rheological Properties of Cellulose Fiber Suspensions". Journal of the Society of Rheology (Japan). 30 (1): 27–32. doi:10.1678/rheology.30.27
  47. ^ Henriksson M, Berglund LA, Isaksson P, Lindström T, Nishino T (June 2008). "Cellulose nanopaper structures of high toughness". Biomacromolecules. 9 (6): 1579–1585. doi:10.1021/bm800038n. PMID 18498189
  48. ^ "Why wood pulp is world's new wonder material – tech – 23 August 2012". New Scientist. Retrieved 2012-08-30.
  49. ^ Mittal N, Ansari F, Gowda VK, Brouzet C, Chen P, Larsson PT, Roth SV, Lundell F, Wågberg L, Kotov NA, Söderberg LD (July 2018). "Multiscale Control of Nanocellulose Assembly: Transferring Remarkable Nanoscale Fibril Mechanics to Macroscale Fibers". ACS Nano. 12 (7): 6378–6388. doi:10.1021/acsnano.8b01084. PMID 29741364
  50. ^ Aulin C, Gällstedt M, Lindström T (2010). "Oxygen and oil barrier properties of microfibrillated cellulose films and coatings". Cellulose. 17 (3): 559–574. doi:10.1007/s10570-009-9393-y
  51. ^ Syverud K, Stenius P (2009). "Strength and barrier properties of MFC films". Cellulose. 16 (1): 75–85. doi:10.1007/s10570-008-9244-2
  52. ^ Chinga-Carrasco G, Syverud K (March 2012). "On the structure and oxygen transmission rate of biodegradable cellulose nanobarriers". Nanoscale Research Letters. 7 (1). Bibcode:2012NRL.....7..192C. doi:10.1186/1556-276X-7-192. PMC 3324384. PMID 22429336
  53. ^ Henriksson M, Berglund L (2007). "Structure and properties of cellulose nanocomposite films containing melamine formaldehyde". Journal of Applied Polymer Science. 106 (4): 2817–2824. Bibcode:2007JAPS..106.2817H. doi:10.1002/app.26946[dead link]
  54. ^ Svagan AJ, Samir MA, Berglund LA (August 2007). "Biomimetic polysaccharide nanocomposites of high cellulose content and high toughness". Biomacromolecules. 8 (8): 2556–2563. doi:10.1021/bm0703160. PMID 17655354
  55. ^ Diddens I, Murphy B, Krisch M, Müller M (2008). "Anisotropic elastic properties of cellulose measured using inelastic x-ray scattering". Macromolecules. 41 (24): 9755–9759. Bibcode:2008MaMol..41.9755D. doi:10.1021/ma801796u
  56. ^ Thielemans W, Warbey CR, Walsh DA (2009). "Permselective nanostructured membranes based on cellulose nanowhiskers". Green Chemistry. 11 (4): 531–537. doi:10.1039/b818056c
  57. ^ Mohan T, Niegelhell K, Zarth CS, Kargl R, Köstler S, Ribitsch V, Heinze T, Spirk S, Stana-Kleinschek K (November 2014). "Triggering protein adsorption on tailored cationic cellulose surfaces". Biomacromolecules. 15 (11): 3931–3941. doi:10.1021/bm500997s. PMID 25233035
  58. ^ Vuoriluoto M, Orelma H, Johansson LS, Zhu B, Poutanen M, Walther A, Laine J, Rojas OJ (December 2015). "Effect of Molecular Architecture of PDMAEMA-POEGMA Random and Block Copolymers on Their Adsorption on Regenerated and Anionic Nanocelluloses and Evidence of Interfacial Water Expulsion". The Journal of Physical Chemistry B. 119 (49): 15275–15286. doi:10.1021/acs.jpcb.5b07628. PMID 26560798
  59. ^ Revol JF, Bradford H, Giasson J, Marchessault RH, Gray DG (June 1992). "Helicoidal self-ordering of cellulose microfibrils in aqueous suspension". International Journal of Biological Macromolecules. 14 (3): 170–172. doi:10.1016/S0141-8130(05)80008-X. PMID 1390450
  60. ^ Nyström G, Arcari M, Adamcik J, Usov I, Mezzenga R (June 2018). "Nanocellulose Fragmentation Mechanisms and Inversion of Chirality from the Single Particle to the Cholesteric Phase". ACS Nano. 12 (6): 5141–5148. arXiv:1705.06620. doi:10.1021/acsnano.8b00512. PMID 29758157
  61. ^ Nordenström M, Fall A, Nyström G, Wågberg L (September 2017). "Formation of Colloidal Nanocellulose Glasses and Gels". Langmuir. 33 (38): 9772–9780. doi:10.1021/acs.langmuir.7b01832. PMID 28853581
  62. ^ Bertsch P, Isabettini S, Fischer P (December 2017). "Ion-Induced Hydrogel Formation and Nematic Ordering of Nanocrystalline Cellulose Suspensions". Biomacromolecules. 18 (12): 4060–4066. doi:10.1021/acs.biomac.7b01119. PMID 29028331
  63. ^ Bertsch P, Schneider L, Bovone G, Tibbitt MW, Fischer P, Gstöhl S (October 2019). "Injectable Biocompatible Hydrogels from Cellulose Nanocrystals for Locally Targeted Sustained Drug Release". ACS Applied Materials & Interfaces. 11 (42): 38578–38585. doi:10.1021/acsami.9b15896. PMID 31573787
  64. ^ Siqueira G, Kokkinis D, Libanori R, Hausmann MK, Gladman AS, Neels A, Tingaut P, Zimmermann T, Lewis JA, Studart AR (March 2017). "Cellulose Nanocrystal Inks for 3D Printing of Textured Cellular Architectures". Advanced Functional Materials. 27 (12). doi:10.1002/adfm.201604619. hdl:20.500.11850/128911
  65. ^ Svagan A, Azizi Samir MA, Berglund LA (2008). "Biomimetic foams of high mechanical performance based on nanostructured cell walls reinforced by native nanofibrils". Advanced Materials. 20 (7): 1263–1269. doi:10.1002/adma.200701215
  66. ^ Pääkkö M, Vapaavuori J, Silvennoinen R, Kosonen H, Ankerfors M, Lindström T, Berglund LA, Ikkala O (2008). "Long and entangled nantive cellulose I nanofibers allow flexible aerogels and hierarchically templates for functionalities". Soft Matter. 4 (12): 2492–2499. Bibcode:2008SMat....4.2492P. doi:10.1039/b810371b
  67. ^ Heath L, Thielemans W (2010). "Cellulose nanowhisker aerogels". Green Chemistry. 12 (8): 1448–1453. doi:10.1039/c0gc00035c
  68. ^ Sehaqui H, Salajková M, Zhou Q, Berglund LA (2010). "Mechanical performance tailoring of tough ultra-high porosity foams prepared from cellulose I nanofiber suspensions". Soft Matter. 6 (8): 1824–1832. Bibcode:2010SMat....6.1824S. doi:10.1039/b927505c
  69. ^ Aulin C, Netrval J, Wågberg L, Lindström T (2010). "Aerogels from nanofibrillated cellulose with tunable oleophobicity". Soft Matter. 6 (14): 3298. Bibcode:2010SMat....6.3298A. doi:10.1039/c001939a
  70. ^ Olsson RT, Azizi Samir MA, Salazar-Alvarez G, Belova L, Ström V, Berglund LA, Ikkala O, Nogués J, Gedde UW (August 2010). "Making flexible magnetic aerogels and stiff magnetic nanopaper using cellulose nanofibrils as templates". Nature Nanotechnology. 5 (8): 584–588. Bibcode:2010NatNa...5..584O. doi:10.1038/nnano.2010.155. PMID 20676090
  71. ^ Kalashnikova I, Bizot H, Cathala B, Capron I (June 2011). "New Pickering emulsions stabilized by bacterial cellulose nanocrystals". Langmuir. 27 (12): 7471–7479. doi:10.1021/la200971f. PMID 21604688
  72. ^ Kalashnikova I, Bizot H, Bertoncini P, Cathala B, Capron I (2013). "Cellulosic nanorods of various aspect ratios for oil in water Pickering emulsions". Soft Matter. 9 (3): 952–959. Bibcode:2013SMat....9..952K. doi:10.1039/C2SM26472B
  73. ^ Bergfreund J, Sun Q, Fischer P, Bertsch P (November 2019). "Adsorption of charged anisotropic nanoparticles at oil-water interfaces". Nanoscale Advances. 1 (11): 4308–4312. Bibcode:2019NanoA...1.4308B. doi:10.1039/C9NA00506D. PMC 9419606. PMID 36134395
  74. ^ Bai L, Lv S, Xiang W, Huan S, McClements DJ, Rojas OJ (November 2019). "Oil-in-water Pickering emulsions via microfluidization with cellulose nanocrystals: 1. Formation and stability". Food Hydrocolloids. 96: 699–708. doi:10.1016/j.foodhyd.2019.04.038. hdl:20.500.14394/29566
  75. ^ Scheuble N, Schaffner J, Schumacher M, Windhab EJ, Liu D, Parker H, Steingoetter A, Fischer P (May 2018). "Tailoring Emulsions for Controlled Lipid Release: Establishing in vitro-in Vivo Correlation for Digestion of Lipids". ACS Applied Materials & Interfaces. 10 (21): 17571–17581. doi:10.1021/acsami.8b02637. PMID 29708724
  76. ^ Bertsch P, Steingoetter A, Arnold M, Scheuble N, Bergfreund J, Fedele S, Liu D, Parker HL, Langhans W, Rehfeld JF, Fischer P (August 2022). "Lipid emulsion interfacial design modulates human in vivo digestion and satiation hormone response". Food & Function. 13 (17): 9010–9020. doi:10.1039/D2FO01247B. hdl:20.500.11850/564599. PMC 9426722. PMID 35942900
  77. ^ Bertsch P, Arcari M, Geue T, Mezzenga R, Nyström G, Fischer P (December 2019). "Designing Cellulose Nanofibrils for Stabilization of Fluid Interfaces". Biomacromolecules. 20 (12): 4574–4580. doi:10.1021/acs.biomac.9b01384. PMID 31714073
  78. ^ Jin H, Zhou W, Cao J, Stoyanov SD, Blijdenstein TB, De Groot PW, Arnaudov LN, Pelan EG (2012). "Super stable foams stabilized by colloidal ethyl cellulose particles". Soft Matter. 8 (7): 2194–2205. Bibcode:2012SMat....8.2194J. doi:10.1039/c1sm06518a
  79. ^ Lee KY, Blaker JJ, Murakami R, Heng JY, Bismarck A (January 2014). "Phase behavior of medium and high internal phase water-in-oil emulsions stabilized solely by hydrophobized bacterial cellulose nanofibrils". Langmuir. 30 (2): 452–460. doi:10.1021/la4032514. PMID 24400918
  80. ^ Saidane D, Perrin E, Cherhal F, Guellec F, Capron I (July 2016). "Some modification of cellulose nanocrystals for functional Pickering emulsions". Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences. 374 (2072). Bibcode:2016RSPTA.37450139S. doi:10.1098/rsta.2015.0139. PMC 4920285. PMID 27298429
  81. ^ Peddireddy KR, Nicolai T, Benyahia L, Capron I (March 2016). "Stabilization of Water-in-Water Emulsions by Nanorods". ACS Macro Letters. 5 (3): 283–286. doi:10.1021/acsmacrolett.5b00953. PMID 35614722
  82. ^ Guan QF, Yang HB, Han ZM, Zhou LC, Zhu YB, Ling ZC, Jiang HB, Wang PF, Ma T, Wu HA, Yu SH (May 2020). "Lightweight, tough, and sustainable cellulose nanofiber-derived bulk structural materials with low thermal expansion coefficient". Science Advances. 6 (18). American Association for the Advancement of Science. Bibcode:2020SciA....6.1114G. doi:10.1126/sciadv.aaz1114. PMC 7195169. PMID 32494670
  83. ^ Eichhorn SJ, Dufresne A, Aranguren M, Marcovich NE, Capadona JR, Rowan SJ, Weder C, Thielemans W, Roman M, Renneckar S, Gindl W, Veigel A, Keckes J, Yano H, Abe AN, Nakagaito A, Mangalam J, Simonsen AS, Benight AS, Bismarck LA, Berglund T (2010). "Review: current international research into cellulose nanofibres and nanocomposites". Journal of Materials Science. 45 (1): 1–33. Bibcode:2010JMatS..45....1E. doi:10.1007/s10853-009-3874-0
  84. ^ Labet M, Thielemans W (2011). "Improving the reproducibility of chemical reactions on the surface of cellulose nanocrystals: ROP of e-caprolactone as a case study". Cellulose. 18 (3): 607–617. doi:10.1007/s10570-011-9527-x
  85. ^ Vartiainen J, Pöhler T, Sirola K, Pylkkänen L, Alenius H, Hokkinen J, Tapper U, Lahtinen P, Kapanen A, Putkisto K, Hiekkataipale P (2011). "Health and environmental safety aspects of friction grinding and spray drying of microfibrillated cellulose". Cellulose. 18 (3): 775–786. doi:10.1007/s10570-011-9501-7
  86. ^ Cao X, Zhang T, DeLoid GM, Gaffrey MJ, Weitz KK, Thrall BD, Qian WJ, Demokritou P (October 2020). "Cytotoxicity and cellular proteome impact of cellulose nanocrystals using simulated digestion and an in vitro small intestinal epithelium cellular model". NanoImpact. 20. Bibcode:2020NanoI..2000269C. doi:10.1016/j.impact.2020.100269
  87. ^ Mortensen NP, Moreno Caffaro M, Davis K, Aravamudhan S, Sumner SJ, Fennell TR (August 2022). "Investigation of eight cellulose nanomaterials' impact on Differentiated Caco-2 monolayer integrity and cytotoxicity". Food and Chemical Toxicology. 166. doi:10.1016/j.fct.2022.113204. PMID 35679974
  88. ^ Lin YJ, Qin Z, Paton CM, Fox DM, Kong F (July 2021). "Influence of cellulose nanocrystals (CNC) on permeation through intestinal monolayer and mucus model in vitro". Carbohydrate Polymers. 263. doi:10.1016/j.carbpol.2021.117984. PMID 33858577
  89. ^ DeLoid GM, Cao X, Molina RM, Silva DI, Bhattacharya K, Ng KW, Loo SC, Brain JD, Demokritou P (July 2019). "Toxicological effects of ingested nanocellulose in in vitro intestinal epithelium and in vivo rat models". Environmental Science: Nano. 6 (7): 2105–2115. doi:10.1039/c9en00184k. hdl:10356/150824. PMC 7055654. PMID 32133146
  90. ^ Ede JD, Ong KJ, Mulenos MR, Pradhan S, Gibb M, Sayes CM, Shatkin JA (December 2020). "Physical, chemical, and toxicological characterization of sulfated cellulose nanocrystals for food-related applications using in vivo and in vitro strategies". Toxicology Research. 9 (6): 808–822. doi:10.1093/TOXRES/TFAA082. PMC 7786165. PMID 33447365
  91. ^ Khare S, DeLoid GM, Molina RM, Gokulan K, Couvillion SP, Bloodsworth KJ, Eder EK, Wong AR, Hoyt DW, Bramer LM, Metz TO, Thrall BD, Brain JD, Demokritou P (April 2020). "Effects of ingested nanocellulose on intestinal microbiota and homeostasis in Wistar Han rats". NanoImpact. 18. Bibcode:2020NanoI..1800216K. doi:10.1016/j.impact.2020.100216. PMC 7080203. PMID 32190784
  92. ^ Brown EE, Hu D, Abu Lail N, Zhang X (April 2013). "Potential of nanocrystalline cellulose-fibrin nanocomposites for artificial vascular graft applications". Biomacromolecules. 14 (4): 1063–1071. doi:10.1021/bm3019467. PMID 23421631
  93. ^ Taipale T, Österberg M, Nykänen A, Ruokolainen J, Laine J (2010). "Effect of microfibrillated cellulose and fines on the drainage of kraft pulp suspension and paper strength". Cellulose. 17 (5): 1005–1020. doi:10.1007/s10570-010-9431-9
  94. ^ Eriksen Ø, Syverud K, Gregersen ØW (2008). "The use of microfibrillated cellulose produced from kraft pulp as strength enhancer in TMP paper". Nordic Pulp & Paper Research Journal. 23 (3): 299–304. doi:10.3183/npprj-2008-23-03-p299-304
  95. ^ Ahola S, Österberg M, Laine J (2007). "Cellulose nanofibrils—adsorption with poly(amideamine) epichlorohydrin studied by QCM-D and application as a paper strength additive". Cellulose. 15 (2): 303–314. doi:10.1007/s10570-007-9167-3
  96. ^ "Paper production". No. US12157974B2.
  97. ^ Syverud K, Stenius P (2008). "Strength and barrier properties of MFC films". Cellulose. 16: 75–85. doi:10.1007/s10570-008-9244-2
  98. ^ Aulin C, Gällstedt M, Lindström T (2010). "Oxygen and oil barrier properties of microfibrillated cellulose films and coatings". Cellulose. 17 (3): 559–574. doi:10.1007/s10570-009-9393-y
  99. ^ Lavoine N, Desloges I, Dufresne A, Bras J (October 2012). "Microfibrillated cellulose - its barrier properties and applications in cellulosic materials: a review". Carbohydrate Polymers. 90 (2): 735–764. doi:10.1016/j.carbpol.2012.05.026. PMID 22839998
  100. ^ Missoum K, Martoïa F, Belgacem MN, Bras J (2013). "Effect of chemically modified nanofibrillated cellulose addition on the properties of fiber-based materials". Industrial Crops and Products. 48: 98–105. doi:10.1016/j.indcrop.2013.04.013
  101. ^ "Heptane Vapor Rate Testing"
  102. ^ "Mineral oil and contaminants: theory and practical solutions for paper & board". Slideshare. Retrieved 2025-11-22.
  103. ^ Kumar V, Elfving A, Koivula H, Bousfield D, Toivakka M (2016-03-30). "Roll-to-Roll Processed Cellulose Nanofiber Coatings". Industrial & Engineering Chemistry Research. 55 (12): 3603–3613. doi:10.1021/acs.iecr.6b00417
  104. ^ Lavoine N, Desloges I, Dufresne A, Bras J (April 2014). "Impact of different coating processes of microfibrillated cellulose on the mechanical and barrier properties of paper". Journal of Materials Science. 49 (7): 2879–2893. Bibcode:2014JMatS..49.2879L. doi:10.1007/s10853-013-7995-0
  105. ^ Mousavi SM, Bousfield D (2016). "Cellulose nanofibers with higher solid content as a coating material to improve structure and barrier properties of paperboard". TAPPI Conference Proceedings
  106. ^ Beneventi D, Chaussy D, Curtil D, Zolin L, Gerbaldi C, Penazzi N (2014-07-09). "Highly Porous Paper Loading with Microfibrillated Cellulose by Spray Coating on Wet Substrates". Industrial & Engineering Chemistry Research. 53 (27): 10982–10989. doi:10.1021/ie500955x
  107. ^ Kinnunen-Raudaskoski K (2014). "Thin coatings for paper by foam coating". TAPPI Journal. 13 (7): 9–19. doi:10.32964/TJ13.7.9
  108. ^ Technologies F (October 2019). "Microfibrillated Cellulose in Barrier Coating Applications". FiberLean Technologies. Retrieved 27 January 2020.
  109. ^ Jung YH, Chang TH, Zhang H, Yao C, Zheng Q, Yang VW, Mi H, Kim M, Cho SJ, Park DW, Jiang H, Lee J, Qiu Y, Zhou W, Cai Z, Gong S, Ma Z (May 2015). "High-performance green flexible electronics based on biodegradable cellulose nanofibril paper". Nature Communications. 6. Bibcode:2015NatCo...6.7170J. doi:10.1038/ncomms8170. PMC 4455139. PMID 26006731
  110. ^ "Threads of nanocellulose stronger than spider silk". 17 October 2018. Retrieved 29 June 2020.
  111. ^ Alves L, Ferraz E, Gamelas JA (October 2019). "Composites of nanofibrillated cellulose with clay minerals: A review". Advances in Colloid and Interface Science. 272. doi:10.1016/j.cis.2019.101994. PMID 31394436
  112. ^ Alves L, Ferraz E, Gamelas JA (2015-08-05). "Composite Films Based on Nanocellulose and Nanoclay Minerals as High Strength Materials with Gas Barrier Capabilities: Key Points and Challenges". BioResources. 10 (4): 6310–6313. doi:10.15376/biores.10.4.6310-6313. hdl:10400.26/38419
  113. ^ Gómez H., C.; Serpa, A.; Velásquez-Cock, J.; Gañán, P.; Castro, C.; Vélez, L.; Zuluaga, R. (June 2016). "Vegetable nanocellulose in food science: A review". Food Hydrocolloids. 57: 178–186. doi:10.1016/j.foodhyd.2016.01.023
  114. ^ Xhanari K, Syverud K, Stenius P (2011). "Emulsions stabilized by microfibrillated cellulose: the effect of hydrophobization, concentration and o/w ratio". Dispersion Science and Technology. 32 (3): 447–452. doi:10.1080/01932691003658942
  115. ^ Lif A, Stenstad P, Syverud K, Nydén M, Holmberg K (December 2010). "Fischer-Tropsch diesel emulsions stabilised by microfibrillated cellulose and nonionic surfactants". Journal of Colloid and Interface Science. 352 (2): 585–592. Bibcode:2010JCIS..352..585L. doi:10.1016/j.jcis.2010.08.052. PMID 20864117
  116. ^ Syverud K, Kirsebom H, Hajizadeh S, Chinga-Carrasco G (December 2011). "Cross-linking cellulose nanofibrils for potential elastic cryo-structured gels". Nanoscale Research Letters. 6 (1). Bibcode:2011NRL.....6..626S. doi:10.1186/1556-276X-6-626. PMC 3260332. PMID 22152032
  117. ^ Granberg H, Håkansson K, Fall A, Wågberg P (5–8 May 2019). Electroactive Papers, Films, Filaments, Aerogels, and Hydrogels to Realize the Future of Bio-based Electronics. 19PaperCon. Indianapolis, USA: TAPPI Press. p. artikel-id PF4.1.
  118. ^ Malti A, Edberg J, Granberg H, Khan ZU, Andreasen JW, Liu X, Zhao D, Zhang H, Yao Y, Brill JW, Engquist I, Fahlman M, Wågberg L, Crispin X, Berggren M (February 2016). "An Organic Mixed Ion-Electron Conductor for Power Electronics". Advanced Science. 3 (2). Bibcode:2016AdvSc...300305M. doi:10.1002/advs.201500305. PMC 5063141. PMID 27774392
  119. ^ Hamedi MM, Hajian A, Fall AB, Håkansson K, Salajkova M, Lundell F, Wågberg L, Berglund LA (March 2014). "Highly conducting, strong nanocomposites based on nanocellulose-assisted aqueous dispersions of single-wall carbon nanotubes". ACS Nano. 8 (3): 2467–2476. doi:10.1021/nn4060368. PMID 24512093
  120. ^ Erlandsson J, López Durán V, Granberg H, Sandberg M, Larsson PA, Wågberg L (2016-12-01). "Macro- and mesoporous nanocellulose beads for use in energy storage devices". Applied Materials Today. 5: 246–254. doi:10.1016/j.apmt.2016.09.008
  121. ^ Nyström G, Marais A, Karabulut E, Wågberg L, Cui Y, Hamedi MM (May 2015). "Self-assembled three-dimensional and compressible interdigitated thin-film supercapacitors and batteries". Nature Communications. 6. Bibcode:2015NatCo...6.7259N. doi:10.1038/ncomms8259. PMC 4458871. PMID 26021485
  122. ^ Wu C, Wang AC, Ding W, Guo H, Wang ZL (2019). "Triboelectric Nanogenerator: A Foundation of the Energy for the New Era". Advanced Energy Materials. 9 (1). Bibcode:2019AdEnM...902906W. doi:10.1002/aenm.201802906
  123. ^ Gray DG, Mu X (November 2015). "Chiral Nematic Structure of Cellulose Nanocrystal Suspensions and Films; Polarized Light and Atomic Force Microscopy". Materials. 8 (11): 7873–7888. Bibcode:2015Mate....8.7873G. doi:10.3390/ma8115427. PMC 5458898. PMID 28793684
  124. ^ Toivonen MS, Onelli OD, Jacucci G, Lovikka V, Rojas OJ, Ikkala O, Vignolini S (April 2018). "Anomalous-Diffusion-Assisted Brightness in White Cellulose Nanofibril Membranes". Advanced Materials. 30 (16). Bibcode:2018AdM....3004050T. doi:10.1002/adma.201704050. PMID 29532967
  125. ^ "Modified bacterial nanocellulose and its uses in chip cards and medicine". No. 2016174104 A1.
  126. ^ "Corrosion inhibitor comprising cellulose nanocrystals and cellulose nanocrystals in combination with a corrosion inhibitor". No. 9222174.
  127. ^ "Use of charged cellulose nanocrystals for corrosion inhibition and a corrosion inhibiting composition comprising the same". No. 9359678.
  128. ^ Kokkonen M, Nelo M, Liimatainen H, Ukkola J, Tervo N, Myllymäki S, Juuti J, Jantunen H (7 February 2022). "Wood-based composite materials for ultralight lens antennas in 6G systems". Materials Advances. 3 (3): 1687–1694. doi:10.1039/D1MA00644D
  129. ^ Dreyfuss-Deseigne, Rémy (2017-01-02). "Nanocellulose Films in Art Conservation: A New and Promising Mending Material for Translucent Paper Objects". Journal of Paper Conservation. 18 (1): 18–29. doi:10.1080/18680860.2017.1334422. ISSN 1868-0860
  130. ^ Völkel, L.; Ahn, K.; Hähner, U.; Gindl-Altmutter, W.; Potthast, A. (2017-06-15). "Nano meets the sheet: adhesive-free application of nanocellulosic suspensions in paper conservation". Heritage Science. 5 (1): 1–17. doi:10.1186/s40494-017-0134-5. ISSN 2050-7445
  131. ^ Henniges, Ute; Angelova, Lora; Schwoll, Sonja; Smith, Holly; Brückle, Irene (2022-01-02). "Microfibrillated cellulose films for mending translucent paper: an assessment of film preparation and treatment application options". Journal of the Institute of Conservation. 45 (1): 36–51. doi:10.1080/19455224.2021.2017314. ISSN 1945-5224
  132. ^ Canham, Robin; Murray, Alison; Hill, Rosaleen (2023-09-01). "Some Practical Aspects of Nanocellulose Film: Characterization, Expansion and Shrinking Tests, and Techniques to Create Remoistenable Nanocellulose". Restaurator. International Journal for the Preservation of Library and Archival Material. 44 (3): 177–203. doi:10.1515/res-2022-0031. ISSN 1865-8431