Mebhydrolin
Verifiedfieldschanged
Watchedfieldschanged
Verifiedrevid462100967
Width200px
Pregnancy categoryNot established[1]
Routes of administrationOral[1]
Legal statusRx-only
Cas number524-81-2
Cas supplemental
6153-33-9 (1,5-naphthalenedisulfonate salt)[2]
Atc prefixR06
Atc suffixAX15
Pubchem22530
Chemspiderid21129
Unii9SUK9B7XVY
KeggD08161
Synonyms9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Iupac name5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
C19
H20
N2
SmilesCN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
Stdinchi1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3
StdinchikeyFQQIIPAOSKSOJM-UHFFFAOYSA-N

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.[4]

References

  1. ^ "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.
  2. ^ "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Archived from the original on January 19, 2016. Retrieved 2007-03-02.
  3. ^ "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  4. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust.. 2 (9): 477–9. doi:10.5694/j.1326-5377.1981.tb112944.x. PMID 6119605. S2CID 11034501