| Verifiedfields | changed |
|---|---|
| Watchedfields | changed |
| Verifiedrevid | 460335745 |
| Iupacname | 3-(3,4-Dihydroxyphenyl)-1-[5-(β-D-glucopyranosyl)-2,4-dihydroxyphenyl]propan-1-one |
| Systematicname | 3-(3,4-Dihydroxyphenyl)-1-{2,4-dihydroxy-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl}propan-1-one |
Aspalathin is a C-linked dihydrochalcone glucoside found in rooibos tea, a herbal tea prepared from the South African rooibos plant, Aspalathus linearis (Fabaceae).[1]
It was first isolated in 1965 by chromatography.[2]
It has demonstrated antidiabetic activity.[3]
References
- ^ Bramati L et al. (2002). "Quantitative Characterization of Flavonoid Compounds in Rooibos Tea (Aspalathus linearis) by LC-UV/DAD". Journal of Agricultural and Food Chemistry. 50 (20): 5513–5519. Elsevier. doi:10.1021/jf025697h. PMID 12236672
- ^ Koeppen, B. H. & Roux, D. G. (June 1966). "C-Glycosylflavonoids. The chemistry of aspalathin". Biochemical Journal. 99 (3): 604–609. doi:10.1042/bj0990604. ISSN 0264-6021. PMC 1265048. PMID 4290475
- ^ Bader, Michael; Mazibuko-Mbeje, Sithandiwe E.; Dludla, Phiwayinkosi V.; Johnson, Rabia; Joubert, Elizabeth; Louw, Johan; Ziqubu, Khanyisani; Tiano, Luca; Silvestri, Sonia; Orlando, Patrick; Opoku, Andy R.; Muller, Christo J. F. (2019). "Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration". PLOS ONE. 14 (5). Bibcode:2019PLoSO..1416172M. doi:10.1371/journal.pone.0216172. ISSN 1932-6203. PMC 6497260. PMID 31048842