ABC-type organic anion transporter ABCA8 is a protein that in humans is encoded by the ABCA8 gene.[1]
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. This protein is a member of the ABCA subfamily. Members of the ABCA subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes.[1]
References
Further reading
- Gerhard DS, Wagner L, Feingold EA (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res.. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334
- Ota T, Suzuki Y, Nishikawa T (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet.. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039
- Mammalian Gene Collection Program Team; Strausberg, R. L.; Feingold, E. A.; Grouse, L. H. et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932
- Tsuruoka S, Ishibashi K, Yamamoto H (2002). "Functional analysis of ABCA8, a new drug transporter.". Biochem. Biophys. Res. Commun.. 298 (1): 41–5. doi:10.1016/S0006-291X(02)02389-6. PMID 12379217
- Iida A, Saito S, Sekine A (2002). "Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.". J. Hum. Genet.. 47 (6): 285–310. doi:10.1007/s100380200041. PMID 12111378
- Harrington JJ, Sherf B, Rundlett S (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol.. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013. S2CID 25064683
- Nagase T, Ishikawa K, Suyama M (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res.. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res.. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548