| Iupac name | (6aR,10R,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromene-1,10-diol |
|---|---|
| Width | 220 |
| Cas number | 24902-23-6 |
| Pubchem | 102506267 |
| Chemspiderid | 58828755 |
| Chembl | 3586106 |
| C | 21 |
| H | 30 |
| O | 3 |
| Smiles | CCCCCC1=CC(=C2[C@H]3[C@@H](CC=C([C@@H]3O)C)C(OC2=C1)(C)C)O |
| Stdinchi | 1S/C21H30O3/c1-5-6-7-8-14-11-16(22)19-17(12-14)24-21(3,4)15-10-9-13(2)20(23)18(15)19/h9,11-12,15,18,20,22-23H,5-8,10H2,1-4H3/t15-,18-,20+/m1/s1 |
| Stdinchikey | KQQMZTULVOWZJR-ZTNFWEORSA-N |
10-Hydroxy-THC (10α-OH-Δ8-THC) is a phytocannabinoid, identified in trace amounts as a component of Cannabis sativa in 2015. It has two epimers, 10α-THC and 10β-THC, of which the α epimer is the pharmacologically active component with similar or slightly higher potency compared to THC itself, while the β epimer is around 100x weaker in vitro and only partially substituted for THC in animal tests.[1] It can also be made synthetically, and has been sold as a designer drug.
See also
- 3'-Hydroxy-THC
- 8-Hydroxyhexahydrocannabinol
- 9-Hydroxyhexahydrocannabinol
- 8,11-Dihydroxytetrahydrocannabinol
- 10-Hydroxy-HHC
- 11-Hydroxy-THC
- 11-Hydroxy-Delta-8-THC
- Cannabiripsol
References
- ^ Radwan MM, ElSohly MA, El-Alfy AT, Ahmed SA, Slade D, Husni AS, Manly SP, Wilson L, Seale S, Cutler SJ, Ross SA (June 2015). "Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa". Journal of Natural Products. 78 (6): 1271–1276. Bibcode:2015JNAtP..78.1271R. doi:10.1021/acs.jnatprod.5b00065. PMC 4880513. PMID 26000707